Tropical and Molecular Parasitology
Seminar Series and Journal Club
Spring 2009

Wednesday - 12:00 Noon
Rm 8101
McDonnell Pediatric Research Building

Please contact the host if you wish to meet with the speaker
Seminar and Journal Club Schedule
Date Speaker & Host Title/Topic


Jan. 28

Speaker: Dr. Gary J. Weil
Host: Weil Lab

Use of advanced surveillance techniques for assessing the impact of mass drug administration on lymphatic filariasis Article: Trends Parasitol. (2007) 23:78-82
PMID: 17174604

Article: PLoS Negl Trop Dis. (2008) 2: e344
PMID: 19065257
Feb. 4

Speaker: Lon-Fye Lye, Ph.D.

Speaker: Matt Kulmann, M.D.
Beverley Lab

Relevance of the diversity among members of the Trypanosoma cruzi trans-sialidase family analyzed with camelids single-domain antibodies

Novel lipid biosynthetic pathways in Leishmania chemotherapeutics

Article: PLoS ONE 2008;3 e3524
PMID: 18949046

Article: EMBO J . (2003) 22: 6016-6026
PMID: 14609948
Feb. 11

Speaker: Asis Khan, Ph.D.

Speaker: Ildiko Dunay, Ph. D.

Sibley Lab

Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells

Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells

Article: Science (2009) 323:530-533
PMID: 19095897

Article: J Exp Med. (2009) Jan 26
[Epub ahead of print] PMID: 19153244

Feb. 18 Speaker: Shalon Babbitt
Goldberg Lab
Starvation Signaling in the Malaria Parasite  
Feb. 25 Speaker: Christopher Armstrong, Ph.D.
Goldberg Lab
Distinct Roles of Plasmodium Rhomboid 1 in Parasite Development and Malaria Pathogenesis Article: PLoS Pathog. (2009) 5 : e1000262
PMID: 19148267
Mar. 4 Speaker: Hongjie Guo, Ph.D.
Beverley Lab
Synthesis of GDP-D-Arabino-pyranose by a Novel bifunctional enzyme and its role in Leishmania biology and parasitism  
Mar. 11 Speaker: Makedonka Mitreva, Ph.D.
Weil Lab
Molecular Determinants Archetypical to the Phylum Nematoda Article: BMC Genomics (2008) 9:525
PMID: 18983679

Article: PLoS Negl Trop Dis. (2008) 2:e269 PMID: 18682827
Mar. 18

Speaker: Alan Fairlamb, Ph.D. (CV)
Beverley Lab

Folate metabolism in African trypanosomes  
Mar. 25

Speaker: Jeffrey S. Buguliskis, Ph.D.
Sibley Lab

The Role of the Intramembrane Protease Rhomboid 4 in Toxoplasma gondii Host Cell Invasion  
Apr. 1 Speaker: Mike Mandell
Beverley Lab
Cholesterol depletion associated with Leishmania major infection alters macrophage CD40 signalosome composition and effector function Article: Nat Immun. (2009) 10:273-80
PMID: 19198591
Apr. 8

Speaker: David Sullivan, Jr., M.D. (CV)

Goldberg Lab

Protean Uses of Approved Clinical Drugs for Protozoan Diseases Article: Antimicrob Agents Chemother. (2008) 52:3106-12
PMID: 18591280

Article: Nature. (2007) 448:645-6
PMID: 17687303

Article: Nat Chem Biol. (2006) 2:415-6
PMID: 16816845
Apr. 15 Speaker: Vasant Muralidharan, Ph.D.
Goldberg Lab
Antigenic variation in Giardia lamblia is regulated by RNA interference Article: Nature. (2008) 456: 750-754
PMID: 19079052
Apr. 22 ***** Special Seminar *****

Speaker: Ashwani Kumar, Ph.D.
Sibley Lab

***** Special Seminar *****
Redox signaling mechanisms involved in Mycobacterium tuberculosis persistence  
Apr. 29

Speaker: Kristen Skillman

Speaker: Michael S. Behnke, Ph.D.

Host: Sibley Lab

Host cell entry by apicomplexa parasites requires actin polymerization in the host cell

Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death

Article: Cell Host Microbe. (2009) 5: 259-272 PMID: 19286135

Article: PLoS Pathog. (2009) 5:e1000288
PMID: 19197351
May 6

Speaker: Nichole Salinas
Host: Tolia Lab

Polymorphisms in erythrocyte binding antigens 140 and 181 affect function and binding but not receptor specificity in Plasmodium falciparum Article: Infect Immun. (2009)771: 689-99
PMID: 19204093


Department of Molecular Microbiology, Box 8230
Center for Infectious Diseases
Washington University School of Medicine
St. Louis, MO 63110-1093 USA