Tropical and Molecular Parasitology
Seminar Series and Journal Club
Spring 2010

Wednesday - 12:00 Noon
Rm 8101
McDonnell Pediatric Research Building

Please contact the host if you wish to meet with the speaker
Seminar and Journal Club Schedule
Date Speaker & Host Title/Topic


Jan. 20 Speaker: Elitza S. Sevova
Host: Sibley Lab

Topics in Trypanosoma brucei:  ER Exit and Sphingolipid Synthesis

Article: Mol Biol Cell. (2009) 20:4739-4750
PMID: 19759175

Article: Mol Micro. (2008) 70: 291-296

Jan. 27 Speaker: Shalon Babbitt
Goldberg Lab
The Toxoplasma Apicoplast Phosphate Translocator Links Cytosolic and Apicoplast Metabolism and Is Essential for Parasite Survival Article: Cell Host Microbe. 2009 Dec 24. [Epub ahead of print]
PMID: 20036630
Feb. 3 Speaker: Matt Kuhlmann, M.D.
Host: Beverley Lab
Synergistic Killing of Leishmania major Involving Lipid Pathway Inhibitors  
Feb. 10

Speaker: Carl Franz
Host: Sibley Lab

Viral Paratransgenesis in the Malaria Vector Anopheles gambiae Article: PLoS Pathog. (2008) 4: e1000135 PMID: 18725926
Feb. 17 Speaker: Peter Fischer, Ph. D.
Host: Weil Lab
Histology of filarial nematodes: detection of neoplasmic tumors and distribution of Wolbachia endobacteria  
Feb. 24 Speaker: Joseph Batchelor
Host: Tolia
Mapping epitopes of the Plasmodium vivax Duffy binding protein with naturally acquired inhibitory antibodies Article: Infect Immun. [Epub ahead of print] PMID: 20008533
Mar. 3 Speaker:
Beverley Lab
Mar. 10 Speaker: Drew Etheridge, Ph.D.

Speaker: Aditi Alagannan
Host: Sibley Lab
A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3

A newly discovered protein export machine in malaria parasites
Article: J. Exp. Med. (2009) 206: 2747-2760 PMID: 19901082

Article: Nature (2009) 459: 945-949
PMID: 19536257
Mar. 17 Speakers: Christina M. Taylor, Ph.D. and
Zhengyuan Wang , Ph.D.
Host: Weil Lab
Pan Phylum specific indels and protein-protein interactions reveal potential drug targets for helminthes  
Mar. 24 Speaker: Cameron M. Douglas, Ph. D. (CV)
Host: Sibley Lab

The “ins” and “outs” of antimicrobial drug discovery at Merck

Mar. 31 Speaker: Luciana Penha, Ph.D.
Host: Beverley Lab
Screening candidate fucosyltransferases for roles in Leishmania survive and virulence Article: FEMS Yeast Res. (2008) 8: 1245 -1253
PMID: 18811659

Article: Glycobiology. (2009) 19:1462-72 PMID: 19696235
Apr. 7

Speaker: Michal Shapira, Ph.D. (CV)
Host: Sibley Lab

Translation regulation in Leishmania - evolutionary divergence of conserved mechanisms Article: RNA. (2010) 16: 364-374
PMID: 20040590

Article: Nucleic Acids Res. (2009) 37: 3243-3253 PMID: 19321500
Apr. 14 Speaker: May M. Paing, Ph.D.
Host: Goldberg Lab

Increased iron stores correlate with worse disease outcomes in a mouse model of schistosomiasis infection

Article: PLoS One (2010) 5:e9594
PMID: 20231891

Apr. 21

Speaker: Michael S. Behnke, Ph.D.

Speaker: Sara Fentress

Host: Sibley Lab

Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

Article: Proc Natl Acad Sci U S A. (2009) 106:19509-19514
PMID: 19858474

Article: Nature. (2010) 464: 728-732 PMID: 20360736

Apr. 28 Speaker: Asis Khan, Ph. D.

Speaker: Sebastian Lourido

Sibley Lab
TgMORN1 is a key organizer for the basal complex of Toxoplasma gondii

Interaction between Plasmodium falciparum apical membrane antigen 1 and the Rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites
Article: PLoS Pathog. (2010) 6: e1000754 PMID: 20140195

Article: J Biol Chem. (2010) [Epub ahead of print]
PMID: 20228060
May 5 Speaker: Vasant Muralidharan, Ph. D.
Goldberg Lab
Ouroboros : Utilizing degradation domains to study Rpn6, a proteasome subunit  


Department of Molecular Microbiology, Box 8230
Center for Infectious Diseases
Washington University School of Medicine
St. Louis, MO 63110-1093 USA