Tropical and Molecular Parasitology
Seminar Series and Journal Club
Spring 2012

Wednesday - 12:00 Noon
Rm 8101
McDonnell Pediatric Research Building

Please contact the host if you wish to meet with the speaker
Seminar and Journal Club Schedules
Date Speaker & Host Title/Topic


Jan. 25

Speaker: Eva Istvan, Ph.D.
Host: Goldberg Lab

Host-mediated regulation of superinfection in malaria

Article: Nat Med. (2011) 17: 732-737
PMID: 21572427

Feb. 1 Speaker: Matt Kuhlmann, M.D.
Host: Beverley Lab
Therapeutic and biological insights learned from drug combination therapy targeting leishmaniasis  
Feb. 8 Speaker: Aditi Alaganan

Speaker: Beth Selleck

Host: Sibley Lab
Juxtamembrane Shedding of Plasmodium falciparum AMA1 Is Sequence Independent and Essential, and Helps Evade Invasion-Inhibitory Antibodies

Independent Roles of Apical Membrane Antigen 1 and Rhoptry Neck Proteins during Host Cell Invasion by Apicomplexa
Article: PLoS Pathog. (2011) 7:e1002448
PMID: 22194692

Article: Cell Host Microbe. (2011) 10:591-602
PMID: 22177563
Feb. 15

Speaker: Gary J. Weil, M.D.
Host: Weil Lab

Applied field research to support the global program to eliminate lymphatic  
Feb. 22

Speaker: Edwin Chen

Speaker: Brian Malpede

Host: Tolia Lab

Conserved and variant epitopes of Plasmodium vivax Duffy binding protein as targets of inhibitory monoclonal antibodies

PfSET10, a Plasmodium falciparum Methyltransferase, Maintains the Active var Gene in a Poised State during Parasite DivisionPfSET10, a Plasmodium falciparum Methyltransferase, Maintains the Active var Gene in a Poised State during Parasite Division

Article: Infect Immun. 2012 Jan 3. [Epub ahead of print]
PMID: 22215740

Article: Cell Host Microbe (2012) 11: 7-18
PMID: 22264509

Feb. 29 Speaker: Miguel Morales, Ph.D. (CV)
Host: Beverley Lab
Dissection of the Leishmania stress response relevant for intracellular infection Article: PNAS. (2010) 107:8381-8386
PMID: 20404152

Article: Eukaryot Cell. (2010) 9: 22-30
PMID: 19801421
Mar. 7

Speaker: Bang Shen, Ph.D.

Speaker: San San Lin, Ph.D.

Host: Sibley Lab

A DOC2 protein identified by mutational profiling is essential for apicomplexan parasite exocytosis

A critical role of perinuclear filamentous actin in spatial repositioning and mutually exclusive expression of virulence genes in malaria parasites
Article: Science. (2012) 335: 218-221
PMID: 22246776

Article: Cell Host Microbe. (2011) 10: 451-463
PMID: 22100161
Mar. 14 Speaker: Stanley Ching-Cheng Huang, Ph.D.
Host: Pearce Lab
The importance of lipid beta-oxidation in Schistosoma mansoni oviposition  
Mar. 21

Speaker: TBA
Host: Goldberg Lab


Mar. 28

Speaker: Michael S. Behnke, Ph.D.
Host: Sibley Lab
Two major virulence factors of Toxoplasma gondii interact to provide resistance to IFN-γ mediated intracellular clearance  
Apr. 4

Speaker: Tamira K. Butler
Host: Beverley Lab

Plasmodium falciparum Inhibitor-3 Homolog Increases Protein Phosphatase Type 1 Activity and Is Essential for Parasitic Survival. Article: J Biol Chem. (2012) 287: 1306-1321
PMID: 22128182
Apr. 11

Speaker: Soojin Jang, Ph.D.
Host: Beverley Lab

Title: Genetic targeting of a complex repetitive locus encoding quinonoid dihydropteridine reductase of Leishmania major  
Apr. 18

Speaker: Asis Khan, Ph.D.
Host: Sibley Lab

Evolution of mono-ChrIa and its role in fixation of population genetic structure of T. gondii  
Apr. 25 Speaker: Paul Sigala, Ph.D.
Host: Goldberg Lab
Porphyrin Metabolism in P. falciparum: Boldly Going Where no Tetrapyrrole Has Gone Before?  
May 2 Speaker: Jason S. Silverman (CV)
Host: Beverley Lab
Form and function in Trypanosoma brucei: the late endosome and the multivesicular body Article: Mol Microbiol. (2011) 82:664-678
PMID: 21923766


Department of Molecular Microbiology, Box 8230
Center for Infectious Diseases
Washington University School of Medicine
St. Louis, MO 63110-1093 USA